Tissue biopsy

PNAClamp™ Mutation Detection Kit TERT

Ref. PNAC-9001

The presence of TERT mutation is a prognostic and predictive biomarker in patients with cancer such as thyroid associated with tumor recurrence and survival.

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About the Product

The presence of TERT mutation is a prognostic and predictive biomarker in patients with cancer such as thyroid associated with tumor recurrence and survival.

With its features of detection limit as low as 5% copies/rxn, the PNAClamp™ TERT Mutation Detection Kit is the qualitative diagnostic test kit which is able to detect 2 different types of TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues using peptide nucleic acid (PNA)-mediated real-time PCR clamping technology.

The PNAClamp™ TERT Mutation Detection Kit is an in vitro diagnostic reagent for detecting 2 different TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from patients with cancer such as thyroid

Technical Characteristics

Mutation C228
  • Nucleotide change: c.1-124C>T
  • c.1-124C>A
Mutation C250 Nucleotide change: c.1-146C>T
Detection limit as low as 5% copies/rxn
Certification CE-IVD (shown only as a badge image CE+IVD.png in DETAILS)
Procedure Sample preparationExtraction of total DNAAmplification of target DNA by Real-Time PCRAnalysis of Result

Key Features

  • Detection of 2 TERT promoter mutations
  • High sensitivity, specificity and reproducibility
  • Short running time
  • Simple workflow
  • Easy result reading by automatic analyzing program

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type:

  • Formalin-fixed paraffin-embedded(FFPE) tissue
  • Fresh tissue and biopsy sample

Compatible Real-Time PCR machine: CFX96 (Bio-Rad)

Packaging

No packaging information available for this product.