PANAMutyper™ Screening Kit ROS1
Ref. PNAR-6001PANAMutyper™ ROS1 Screening Kit is the qualitative diagnostic test kit which is able to detect 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR…
About the Product
PANAMutyper™ ROS1 Screening Kit is the qualitative diagnostic test kit which is able to detect 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system.
The PANAMutyper™ ROS1 Screening Kit is intended as an aid for screening ROS1 fusion-positive NSCLC patients who would be sensitive for receiving ROS1 inhibitor therapy such as crizotinib, Lorlatinib, etc.
The PANAMutyper™ ROS1 Screening Kit is an invitro diagnostic device for detecting 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.
Technical Characteristics
| ROS1 Fusion Types | 1 CD6-R32 | 2 CD6-R34 | 3 EZ10-R34 | 4 SL4-R32 | 5 SL4-R34 | 6 SL13del-R32 | 7 SL13del-R34 | 8 SD2-R34 | 9 SD2-R34 | 10 SD4-R32 | 11 SD4-R34 | 12 TP2-R35 | 13 TP2-R36 | 14 TP8-R35 | 15 TP8-R36 | 16 GO4-R35 | 17 GO4-R36 | 18 GO8-R35 | 19 GO8-R36 | 20 LR16-R35 |
|---|---|
| Fusion partners (last observed exon) | CD74 (exon 6)EZR (exon 10)SLC34A2 (exon 4, exon 13del)SDC4 (exon 2, exon 4)TPM3 (exon 2, exon 8)GOPC (exon 4, exon 8)LRIG3 (exon 16) |
| ROS1 first observed exon | exon 32, 34, 35, 36 |
| Procedure | Extraction of total RNAPCR preparationReal-time PCR(RT)Analysis of result |
Key Features
- One-step RT-PCR technology
- Detection of 20 ROS1 fusion gene variants in two tube reaction
- High sensitivity, specificity and reproducibility
- Short running time
- Simple workflow
- Easy result reading by automatic analyzing program
Technical Information
No technical information available for this product.
Compatibility
Compatible sample type:
- Formalin-fixed paraffin-embedded(FFPE) tissue
- Fresh tissue and biopsy
Compatible Real-Time PCR machine:
- CFX96 (Bio-Rad)
- QuantStudio5 (Thermo Fisher Scientific)
Packaging
No packaging information available for this product.