Molecular

PANAMutyper™ Screening Kit EML4-ALK

Ref. PNAR-5001

Tests per card —

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About the Product

PANAMutyper™ EML4-ALK Screening Kit is the qualitative diagnostic test kit which is able to detect 16 different EML4-ALK fusion genes of tissue from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system. The PANAMutyper™ EML4-ALK Screening Kit is intended as an aid for screening EML4-ALK fusion-positive NSCLC patients who would be sensitive for receiving ALK inhibitor therapy such as crizotinib.

The PANAMutyper™ EML4-ALK Screening Kit is an in vitro diagnostic reagent for detecting 16 different EML4-ALK fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.

Key Features

One-step RT-PCR technology
Detection of 16 EML4-ALK fusion gene variants in one tube reaction
High sensitivity, specificity and reproducibility
Short running time
Simple workflow
Easy result reading by automatic analyzing program

Technical Characteristics

EML4-ALK Fusion Types	1 E2;A20 \| 2 E2;ins117A20 \| 3 E6;A20 \| 4 E6ins33;A20 \| 5 E6;ins18A20 \| 6 E6;A19 \| 7 E13;ins69A20 \| 8 E13;A20 \| 9 E14ins11;del49A20 \| 10 E14;del14A20 \| 11 E14ins2;ins56A20 \| 12 E17;ins30A20 \| 13 E17ins61;ins34A20 \| 14 E18;A20 \| 15 E20;A20 \| 16 E20;ins18A20
Procedure	Total RNA extraction > Sample preperation > RT-PCR(real-time) > Analysis of result

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type:

Formalin-fixed paraffin-embedded(FFPE) tissue
Fresh tissue and biopsy sample

Compatible Real-Time PCR machine:

CFX96 (Bio-Rad)
QuantStudio5 (ThermoFisher Scientific)

Packaging

No packaging information available for this product.