OncoTector™ ROS1 Fusion Detection Kit
Ref. PNAA-6001OncoTector™ ROS1 Fusion Detection Kit is a qualitative test product based on PNA-mediated real-time PCR technology, capable of detecting 14 types of ROS1 gene fusions from tumor tissue samples of non-small cell lung cancer patients.
About the Product
OncoTector™ ROS1 Fusion Detection Kit is a qualitative test product based on PNA-mediated real-time PCR technology, capable of detecting 14 types of ROS1 gene fusions from tumor tissue samples of non-small cell lung cancer patients.
The OncoTector™ ROS1 Fusion Detection Kit can help identify patients with the ROS1 gene fusion in order to support prescription of Xalkori (Crizotinib), a targeted therapy for lung cancer patients.
Key Features
- Detect 14 types of ROS1 gene fusions using 2 reaction tubes
- One-step reverse-transcription qPCR
- High sensitivity and specificity
- Convenient testing with master mix format
- Automated result analysis software
Technical Characteristics
| ROS1 Fusion type 1 | CD74 (exon 6) ; ROS1 (exon 32) |
|---|---|
| ROS1 Fusion type 2 | CD74 (exon 6) ; ROS1 (exon 34) |
| ROS1 Fusion type 3 | EZR (exon 10) ; ROS1 (exon 34) |
| ROS1 Fusion type 4 | SLC34A2 (exon 4) ; ROS1 (exon 32) |
| ROS1 Fusion type 5 | SLC34A2 (exon 4) ; ROS1 (exon 34) |
| ROS1 Fusion type 6 | SLC34A2 (exon 13 del) ; ROS1 (exon 32) |
| ROS1 Fusion type 7 | SLC34A2 (exon 13 del) ; ROS1 (exon 34) |
| ROS1 Fusion type 8 | SDC4 (exon 2) ; ROS1 (exon 32) |
| ROS1 Fusion type 9 | SDC4 (exon 4) ; ROS1 (exon 32) |
| ROS1 Fusion type 10 | SDC4 (exon 4) ; ROS1 (exon 34) |
| ROS1 Fusion type 11 | TPM3 (exon 8) ; ROS1 (exon 35) |
| ROS1 Fusion type 12 | GOPC (exon 8) ; ROS1 (exon 35) |
| ROS1 Fusion type 13 | GOPC (exon 4) ; ROS1 (exon 36) |
| ROS1 Fusion type 14 | LRIG3 (exon 16) ; ROS1 (exon 35) |
| Procedure | RNA Extraction > PCR Setup > Real-time PCR > Result Analysis |
Technical Information
No technical information available for this product.
Compatibility
Compatible sample type: Formalin-fixed paraffin-embedded (FFPE) tissue
Compatible Real-Time PCR machine: CFX96 (Bio-Rad)
Packaging
No packaging information available for this product.