OncoTector™ KRAS Mutation Detection Kit
Ref. PNAA-2001OncoTector™ KRAS Mutation Detection Kit is a qualitative test product based on PNA-medated real-time PCR technology, capable of detecting 8 types of KRAS gene mutations from tumor tissue samples of non-small cell lung cancer patients.
About the Product
OncoTector™ KRAS Mutation Detection Kit is a qualitative test product based on PNA-medated real-time PCR technology, capable of detecting 8 types of KRAS gene mutations from tumor tissue samples of non-small cell lung cancer patients.
The OncoTector™ KRAS Mutation Detection Kit can help identify patients with the KRAS G12C mutation in order to support prescription of LUMAKRAS™ (Sotorasib), a targeted therapy for lung cancer patients.
Key Features
- Detection of 8 major KRAS codon 12 and 13 mutation genotypes
- Distinguish 8 genotypes using 4 reaction tubes
- High sensitivity and specificity
- Convenient testing with master mix format
- Automated result analysis software
Technical Characteristics
| KRAS mutation 1 | Amino acid change: p.G12C; Nucleotide change: c.34G>T |
|---|---|
| KRAS mutation 2 | Amino acid change: p.G12D; Nucleotide change: c.35G>A |
| KRAS mutation 3 | Amino acid change: p.G13C; Nucleotide change: c.37G>T |
| KRAS mutation 4 | Amino acid change: p.G12V; Nucleotide change: c.35G>T |
| KRAS mutation 5 | Amino acid change: p.G12S; Nucleotide change: c.34G>A |
| KRAS mutation 6 | Amino acid change: p.G12A; Nucleotide change: c.35G>C |
| KRAS mutation 7 | Amino acid change: p.G13D; Nucleotide change: c.38G>A |
| KRAS mutation 8 | Amino acid change: p.G12R; Nucleotide change: c.34G>C |
| Procedure | DNA Extraction > PCR Setup > Real-time PCR > Result Analysis |
Technical Information
No technical information available for this product.
Compatibility
Compatible sample type: Formalin-fixed paraffin-embedded (FFPE) tissue
Compatible Real-Time PCR machine: CFX96 (Bio-Rad)
Packaging
No packaging information available for this product.