OncoTector™ BRAF Mutation Detection Kit
Ref. PNAA-1001OncoTector™ BRAF Mutation Detection Kit is a qualitative in vitro diagnostic test designed to detect BRAF mutations in biopsy tissue, formalin-fixed paraffin-embedded (FFPE) tissue, and thyroid fine-needle aspiration biopsy (FNAB) specimens by peptide nucleic acid (PNA)-mediated mutant-specific amplification.
About the Product
OncoTector™ BRAF Mutation Detection Kit is a qualitative in vitro diagnostic test designed to detect BRAF mutations in biopsy tissue, formalin-fixed paraffin-embedded (FFPE) tissue, and thyroid fine-needle aspiration biopsy (FNAB) specimens by peptide nucleic acid (PNA)-mediated mutant-specific amplification.
The OncoTector™ BRAF Mutation Detection Kit is intended to aid in the identification of patients with thyroid cancer, non-small cell lung cancer (NSCLC), or colorectal cancer who may benefit from BRAF inhibitor therapy.
Key Features
- Detection of 2 major BRAF exon 15 mutation genotypes
- Distinguish 2 genotypes using 1 reaction tubes
- High sensitivity and specificity
- Convenient testing with master mix format
- Automated result analysis software
Technical Characteristics
| BRAF Mutation 1 | Amino Acid Change: p.V600E; Nucleotide change: c.1799T>A |
|---|---|
| BRAF Mutation 2 | Amino Acid Change: p.V600E; Nucleotide change: c.1799_1800delinsAA |
| Procedure | DNA Extraction > PCR Setup > Real-time PCR > Result Analysis |
Technical Information
No technical information available for this product.
Compatibility
Compatible sample type:
- biopsy tissue
- Formalin-fixed paraffin-embedded (FFPE) tissue
- fine needle aspiration biopsy (FNAB)
Compatible Real-Time PCR machine:
- CFX96 (Bio-Rad)
- ABI 7500 Fast
- Light Cycler® 480 II
- Rotor-Gene Q
- QuantStudio® 5
- StepOnePlus™
Packaging
No packaging information available for this product.