PANAMutyper™ Screening Kit ROS1
Molecular

PANAMutyper™ Screening Kit ROS1

Ref. PNAR-6001

PANAMutyper™ ROS1 Screening Kit is the qualitative diagnostic test kit which is able to detect 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR…

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About the Product

PANAMutyper™ ROS1 Screening Kit is the qualitative diagnostic test kit which is able to detect 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system.

The PANAMutyper™ ROS1 Screening Kit is intended as an aid for screening ROS1 fusion-positive NSCLC patients who would be sensitive for receiving ROS1 inhibitor therapy such as crizotinib, Lorlatinib, etc.

The PANAMutyper™ ROS1 Screening Kit is an invitro diagnostic device for detecting 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.

Key Features

  • One-step RT-PCR technology
  • Detection of 20 ROS1 fusion gene variants in two tube reaction
  • High sensitivity, specificity and reproducibility
  • Short running time
  • Simple workflow
  • Easy result reading by automatic analyzing program

Technical Characteristics

ROS1 Fusion Types 1 CD6-R32 | 2 CD6-R34 | 3 EZ10-R34 | 4 SL4-R32 | 5 SL4-R34 | 6 SL13del-R32 | 7 SL13del-R34 | 8 SD2-R34 | 9 SD2-R34 | 10 SD4-R32 | 11 SD4-R34 | 12 TP2-R35 | 13 TP2-R36 | 14 TP8-R35 | 15 TP8-R36 | 16 GO4-R35 | 17 GO4-R36 | 18 GO8-R35 | 19 GO8-R36 | 20 LR16-R35
Fusion partners (last observed exon) CD74 (exon 6); EZR (exon 10); SLC34A2 (exon 4, exon 13del); SDC4 (exon 2, exon 4); TPM3 (exon 2, exon 8); GOPC (exon 4, exon 8); LRIG3 (exon 16)
ROS1 first observed exon exon 32, 34, 35, 36
Procedure Extraction of total RNA > PCR preparation > Real-time PCR(RT) > Analysis of result

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type:

  • Formalin-fixed paraffin-embedded(FFPE) tissue
  • Fresh tissue and biopsy

Compatible Real-Time PCR machine:

  • CFX96 (Bio-Rad)
  • QuantStudio5 (Thermo Fisher Scientific)

Packaging

No packaging information available for this product.