Tissue biopsy

PANAMutyper™ Screening Kit EML4-ALK

Ref. PNAR-5001

PANAMutyper™ EML4-ALK Screening Kit is the qualitative diagnostic test kit which is able to detect 16 different EML4-ALK fusion genes of tissue from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system.

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Contact us for product availability and technical details.

About the Product

PANAMutyper™ EML4-ALK Screening Kit is the qualitative diagnostic test kit which is able to detect 16 different EML4-ALK fusion genes of tissue from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system. The PANAMutyper™ EML4-ALK Screening Kit is intended as an aid for screening EML4-ALK fusion-positive NSCLC patients who would be sensitive for receiving ALK inhibitor therapy such as crizotinib.

The PANAMutyper™ EML4-ALK Screening Kit is an in vitro diagnostic reagent for detecting 16 different EML4-ALK fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.

Technical Characteristics

EML4-ALK Fusion Types 1 E2A20 | 2 E2ins117A20 | 3 E6A20 | 4 E6ins33A20 | 5 E6ins18A20 | 6 E6A19 | 7 E13ins69A20 | 8 E13A20 | 9 E14ins11del49A20 | 10 E14del14A20 | 11 E14ins2ins56A20 | 12 E17ins30A20 | 13 E17ins61ins34A20 | 14 E18A20 | 15 E20A20 | 16 E20ins18A20
Procedure Total RNA extractionSample preperationRT-PCR(real-time)Analysis of result

Key Features

  • One-step RT-PCR technology
  • Detection of 16 EML4-ALK fusion gene variants in one tube reaction
  • High sensitivity, specificity and reproducibility
  • Short running time
  • Simple workflow
  • Easy result reading by automatic analyzing program

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type:

  • Formalin-fixed paraffin-embedded(FFPE) tissue
  • Fresh tissue and biopsy sample

Compatible Real-Time PCR machine:

  • CFX96 (Bio-Rad)
  • QuantStudio5 (ThermoFisher Scientific)

Packaging

No packaging information available for this product.