PNAClamp™ Mutation Detection Kit c-KIT
Ref. PNAC-8001C-kit (also called CD117) may also be found in higher than normal amounts, or in a changed form, on some types of cancer cells, including gastrointestinal stromal tumors and melanoma. Measuring the amount of c-kit in tumor tissue may help diagnose cancer and plan treatment.
About the Product
C-kit (also called CD117) may also be found in higher than normal amounts, or in a changed form, on some types of cancer cells, including gastrointestinal stromal tumors and melanoma. Measuring the amount of c-kit in tumor tissue may help diagnose cancer and plan treatment. C-kit is a type of receptor tyrosine kinase and a type of tumor marker.
Total 5 c-KIT can be detected.
Technical Characteristics
| Mutations - Codon 816 | 5 |
|---|---|
| Total mutations | 5 |
| Detection limit | 2% LOD with 10 ng wild/mutant type mixed DNA |
| Running time | within 3 hours |
| Procedure | Sample PreparationExtraction of Total DNAReal-Time PCRAnalysis of Result |
Key Features
- High sensitivity and specificity even with small amount of DNA (2% LOD with 10 ng wild/mutant type mixed DNA)
- Real-Time PCR based ready-to-use kit
- Short running time (within 3 hours)
Technical Information
No technical information available for this product.
Compatibility
Compatible sample type:
- FFPE tissue
- Biopsy tissue
Compatible Real-Time PCR machine:
- CFX96 (Bio-Rad)
- QuantStudio5 (Thermo Fisher Scientific)
- LightCycler 480II (Roche)
- ABI7500 (Thermo Fisher Scientific)
- ABI7900HT (Thermo Fisher Scientific)
- StepOnePlus (Thermo Fisher Scientific)
- Rotor-Gene Q (Qiagen)
Packaging
25 tests