Tissue biopsy

OncoTector™ KRAS Mutation Detection Kit

Ref. PNAA-2001

OncoTector™ KRAS Mutation Detection Kit is a qualitative test product based on PNA-medated real-time PCR technology, capable of detecting 8 types of KRAS gene mutations from tumor tissue samples of non-small cell lung cancer patients.

Tests per card —

Packaging —

Request a Consultation Download Brochure

About the Product

The OncoTector™ KRAS Mutation Detection Kit can help identify patients with the KRAS G12C mutation in order to support prescription of LUMAKRAS™ (Sotorasib), a targeted therapy for lung cancer patients.

Technical Characteristics

KRAS mutation 1	Amino acid change: p.G12C Nucleotide change: c.34G>T
KRAS mutation 2	Amino acid change: p.G12D Nucleotide change: c.35G>A
KRAS mutation 3	Amino acid change: p.G13C Nucleotide change: c.37G>T
KRAS mutation 4	Amino acid change: p.G12V Nucleotide change: c.35G>T
KRAS mutation 5	Amino acid change: p.G12S Nucleotide change: c.34G>A
KRAS mutation 6	Amino acid change: p.G12A Nucleotide change: c.35G>C
KRAS mutation 7	Amino acid change: p.G13D Nucleotide change: c.38G>A
KRAS mutation 8	Amino acid change: p.G12R Nucleotide change: c.34G>C
Procedure	DNA ExtractionPCR SetupReal-time PCRResult Analysis

Key Features

Detection of 8 major KRAS codon 12 and 13 mutation genotypes
Distinguish 8 genotypes using 4 reaction tubes
High sensitivity and specificity
Convenient testing with master mix format
Automated result analysis software

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type: Formalin-fixed paraffin-embedded (FFPE) tissue

Compatible Real-Time PCR machine: CFX96 (Bio-Rad)

Packaging

No packaging information available for this product.