Tissue biopsy

OncoTector™ BRAF Mutation Detection Kit

Ref. PNAA-1001

OncoTector™ BRAF Mutation Detection Kit is a qualitative in vitro diagnostic test designed to detect BRAF mutations in biopsy tissue, formalin-fixed paraffin-embedded (FFPE) tissue, and thyroid fine-needle aspiration biopsy (FNAB) specimens by peptide nucleic acid (PNA)-mediated mutant-specific amplification.

Tests per card —
Packaging —
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About the Product

OncoTector™ BRAF Mutation Detection Kit is a qualitative in vitro diagnostic test designed to detect BRAF mutations in biopsy tissue, formalin-fixed paraffin-embedded (FFPE) tissue, and thyroid fine-needle aspiration biopsy (FNAB) specimens by peptide nucleic acid (PNA)-mediated mutant-specific amplification.

The OncoTector™ BRAF Mutation Detection Kit is intended to aid in the identification of patients with thyroid cancer, non-small cell lung cancer (NSCLC), or colorectal cancer who may benefit from BRAF inhibitor therapy.

Technical Characteristics

BRAF Mutation 1
  • Amino Acid Change: p.V600E
  • Nucleotide change: c.1799T>A
BRAF Mutation 2
  • Amino Acid Change: p.V600E
  • Nucleotide change: c.1799_1800delinsAA
Procedure DNA ExtractionPCR SetupReal-time PCRResult Analysis

Key Features

  • Detection of 2 major BRAF exon 15 mutation genotypes
  • Distinguish 2 genotypes using 1 reaction tubes
  • High sensitivity and specificity
  • Convenient testing with master mix format
  • Automated result analysis software

Technical Information

No technical information available for this product.

Compatibility

Compatible sample type:

  • biopsy tissue
  • Formalin-fixed paraffin-embedded (FFPE) tissue
  • fine needle aspiration biopsy (FNAB)

Compatible Real-Time PCR machine:

  • CFX96 (Bio-Rad)
  • ABI 7500 Fast
  • Light Cycler® 480 II
  • Rotor-Gene Q
  • QuantStudio® 5
  • StepOnePlus™

Packaging

No packaging information available for this product.